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Hemolytisk-uremisk syndrom

Ulike blodsykdommer

Pasientinformasjon

Blod

Kliniske kapitler

Håndboken

Norsk Elektronisk Legehåndbok

Hva er hemolytisk-uremisk syndrom (HUS)?

Årsak

Diagnostikk

Behandling

Forebygging

EHEC-infeksjoner og barnehager

Prognose

--&gt; http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Search&amp;db=PubMed&amp;term=36272423[uid]

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--&gt; http://dx.doi.org/10.1056/NEJMra2108739

Freedman SB, van de Kar NCAJ, Tarr PI. Shiga Toxin–Producing Escherichia coli and the Hemolytic–Uremic Syndrome. Review article. N Engl J Med 2023; 389: 1402-1414. doi:10.1056/NEJMra2108739 

Noris M, Remuzzi G. Atypical hemolytic-uremic syndrome. N Engl J Med 2009; 361: 1676-87. 

Klein EJ, Stapp JR, Clausen CR, et al. Shiga toxin-producing Escherichia coli in children with diarrhea: a prospective point of care study. J Pediatr 2002; 141: 172-77. 

Andreoli SP. The pathophysiology of the hemolytic uremic syndrome. Curr Opin Nephrol Hypertens 1999; 8: 459-64. 

Index of suspicion. Pediatr Rev 2002; 23: 433-8. 

--&gt; https://fhi.no/nettpub/smittevernveilederen/sykdommer-a-a/e.-coli-enteritt-inkludert-ehec-inf/

Folkehelseinstituttet. Smittevernveilederen. E. coli-enteritt (inkludert EHEC-infeksjon og HUS) - veileder for helsepersonell. Smittevernveilederen, sist oppdatert 25.04.2022. Siden lest 11.11.2022 

Williams DM, Sreedhar SS, Mickell JJ, Chan JC. Acute kidney failure: a pediatric experience over 20 years. Arch Pediatr Adolesc Med 2002; 156: 893-900. 

Andreoli SP. Acute renal failure. Curr Opin Pediatr 2002; 14: 183-8. 

Wong CS, Jelacic S, Habeeb RL, Watkins SL, Tarr PI. The risk of the hemolytic-uremic syndrome after antibiotic treatment of Escherichia coli O157:H7 infections. N Engl J Med 2000; 342: 1930-6. 

Chandler WL, Jelacic B, Boster DR, et al. Prothrombotic coagulation abnormalities associated with Escherichia coli O157:H7 infections. N Engl J Med 2002; 346: 23-32. 

Piercefield EW, Bradley KK, Coffman RL, Mallonee SM. Hemolytic uremic syndrome after an Eschericia coli O111 outbreak. Arch Intern Med 2010; 170: 1656-63. 

Razzaq S. Hemolytic uremic syndrome: An emerging health risk. Am Fam Physician 2006; 74: 991-6. 

--&gt; https://www.fhi.no/nyheter/2023/alvorlig-e.-coli-utbrudd-er-ikke-over

Folkehelseinstituttet. Alvorlig E.coli-utbrudd er ikke over. Nyhetssak 10.10.2023. 

Baylis CL, MacPhee S, Robinson AJ, Griffiths R, Lilley K, Betts RP. Survival of Escherichia coli O157:H7, O111:H- and O26:H11 in artificially contaminated chocolate and confectionery products. Int J Food Microbiol 2004; 96: 35-48. 

Richardson SE, Karmali MA, Becker LE, Smith CR. The histopathology of the hemolytic uremic syndrome associated with verocytotoxin-producing Escherichia coli infections. Hum Pathol 1998; 19: 1102-08. 

Thorpe CM. Shiga toxin-producing Escherichia coli infection. Clin Infect Dis 2004; 38: 1298-303. 

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Kakoullis L, Papachristodoulou E, Chra P, Panos G, et al. Shiga toxin-induced haemolytic uraemic syndrome and the role of antibiotics: a global overview. J Infect. 2019; 79: 75-94. PMID: 31150744 

Bayat A, Rittig S. Hæmolytisk uræmisk syndrom hos børn. Ugeskr Læger 2012; 174: 1302. 

--&gt; http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Search&amp;db=PubMed&amp;term=30382336[uid]

Khalid M, Andreoli S. Extrarenal manifestations of the hemolytic uremic syndrome associated with Shiga toxin-producing Escherichia coli (STEC HUS). Pediatr Nephrol. 2019; 34: 2495-2507. PMID: 30382336 

Michael M, Elliott EJ, Ridley GF, Hodson EM, Craig JC. Interventions for haemolytic uraemic syndrome and thrombotic thrombocytopenic purpura. Cochrane Database of Systematic Reviews 2009, Issue 1. Art. No.: CD003595. DOI: 10.1002/14651858.CD003595.pub2. 

--&gt; http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Search&amp;db=PubMed&amp;term=34871193[uid]

Tarr PI, Freedman SB. Why antibiotics should not be used to treat Shiga toxin-producing Escherichia coli infections. Curr Opin Gastroenterol. 2022; 38: 30-38. PMID: 34871193 

Tarr PI, Gordon CA, Chandler WL. Shiga-toxin-producing Escherichia coli and haemolytic uraemic syndrome. Lancet 2005; 365: 1073-86. 

--&gt; http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Search&amp;db=PubMed&amp;term=25651368[uid]

Licht C, Greenbaum LA, Muus P, et al. Efficacy and safety of eculizumab in atypical hemolytic uremic syndrome from 2-year extensions of phase 2 studies. Kidney Int. 2015; 87: 1061-1073. PMID: 25651368 

--&gt; http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Search&amp;db=PubMed&amp;term=32299680[uid]

Rondeau E, Scully M, Ariceta G, et al. The long-acting C5 inhibitor, ravulizumab, is effective and safe in adult patients with atypical hemolytic uremic syndrome naïve to complement inhibitor treatment. Kidney Int. 2020; 97: 1287-1296. PMID: 32299680 

Hemolytisk-uremisk syndrom (HUS)

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