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Acetylcystein

Acetylcystein brukes som motgift ved forgiftninger med paracetamol. Men acetylcystein har også vist seg å virke ved en rekke andre tilstander.

Sist revidert:

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Del pasientinformasjon

Den ligger åpent tilgjengelig på NHI.no sammen annen relevant informasjon

https://nhi.no/forstehjelp/forgiftninger/acetylcystein/ 

Kroniske luftveissykdommer

Kontrastindusert nyreskade

Influensa

Andre tilstander

Bivirkninger

Oppsummert

Kilder

Referanser

  1. Chiew AL, Gluud C, Brok J, Buckley NA. Interventions for paracetamol (acetaminophen) overdose. Cochrane Database of Systematic Reviews 2018, Issue 2. Art. No.: CD003328. The Cochrane Library  
  2. Millea PJ. N-acetylcysteine: multiple clinical applications. Am Fam Physician 2009; 80: 265-9. American Family Physician  
  3. Dekhuijzen PN. Antioxidant properties of N-acetylcysteine: their relevance in relation to chronic obstructive pulmonary disease. Eur Respir J 2004; 23: 629–36.
  4. Dickinson DA, Moellering DR, Iles KE, et al. Cytoprotection against oxidative stress and the regulation of glutathione synthesis. Biol Chem 2003; 384: 527–37.
  5. Cazzola M, Calzetta L, Page C, et al. Influence of N-acetylcysteine on chronic bronchitis or COPD exacerbations: a meta-analysis. Eur Respir Rev. 2015;24(137):451-461. PMID: 26324807. PubMed  
  6. Stey C, Steurer J, Bachmann S, Medici TC, Tramür MR. The effect of oral N-acetylcysteine in chronic bronchitis: a quantitative systematic review. Eur Respir J 2000; 16: 253–62.
  7. Decramer M, Ruttenvan Molken M, Dekhuijzen PN, et al. Effects of N-acetylcysteine on outcomes in chronic obstructive pulmonary disease (Bronchitis Randomized on NAC Cost-Utility Study, BRONCUS): a randomised placebo-controlled trial. Lancet 2005; 365: 1552–60.
  8. Rihal CS, Textor SC, Grill DE, et al. Incidence and prognostic importance of acute renal failure after percutaneous coronary intervention. Circulation 2002; 105: 2259–64.
  9. Van Praet JT, De Vriese AS. Prevention of contrast-induced nephropathy: a critical review. Curr Opin Nephrol Hypertens 2007; 16: 336–47.
  10. Trivedi H, Daram S, Szabo A, Bartorelli AL, Marenzi G. High-dose N-acetylcysteine for the prevention of contrast-induced nephropathy. Am J Med 2009; 122: 874.e9-15.
  11. Demedts M, Behr J, Buhl R, et al., for the IFIGENIA Study Group. High-dose acetylcysteine in idiopathic pulmonary fibrosis. N Engl J Med 2005; 353: 2229–42.