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Kondylomer

Sist oppdatert: Sist revidert:
Sist revidert av:
Definisjon:
Kondylomer (kjønnsvorter) er små vorter lokalisert på eller rundt kjønnsorganer eller endetarm. Forårsakes av HPV type 6 og 11, og overføres seksuelt
Forekomst:
Svært hyppig og ses oftest i aldersgruppen 18-26 år
Symptomer:
Utvendige vorter er synlige, men gir vanligvis ingen plager. Men de kan irritere og blø ved mekanisk påkjenning
Funn:
Utseende er typisk med 1-3 mm store utvekster med hudfarget eller hvit, og litt ruglete overflate. Lokalisert særlig i bakre kommissur, ev. innover i vagina, men kan finnes i hele vulva
Diagnostikk:
Diagnosen stilles på grunn av vortenes utseende, og tilleggsundersøkelser er ikke nødvendig
Behandling:
Lokal påsmøring av cytotoksiske eller immundempende midler, ev. kryoterapi, laserkirurgi eller elektrodisseksjon. Forebygges med bruk av kondom. Kvadrivalent HPV-vaksine beskytter
  1. Karnes JB, Usatine RP. Management of external genital warts. Am Fam Physician. 2014 Sep 1;90(5):312-8. PMID: 25251091. PubMed  
  2. Woodhall S, Ramsey T, Cai C, et al. Estimation of the impact of genital warts on health-related quality of life published correction appears in Sex Transm Infect. 2008;84(4):328. Sex Transm Infect. 2008; 84(3):161–166.
  3. Buck HW. Warts (genital). Clinical Evidence 2010; 8: 1602. Clinical Evidence  
  4. Chow EPF, Carter A, Vickers T, et al. Effect on genital warts in Australian female and heterosexual male individuals after introduction of the national human papillomavirus gender-neutral vaccination programme: an analysis of national sentinel surveillance data from 2004–18. Lancet Infect Dis 2021. pmid:34339639 PubMed  
  5. Sexually transmitted diseases treatment guidelines 2002. Centers for Disease Control and Prevention. MMWR Recomm Rep 2002; 51: 1-78. PubMed  
  6. Bouvard V, Baan R, Straif K, et al. A review of human carcinogens-Part B: biological agents. Lancet Oncology 2009; 10: 321-2. doi:10.1016/S1470-2045(09)70096-8. PMID: 19350698 PubMed  
  7. Forcier M, Musacchio N. An overview of human papillomavirus infection for the dermatologist: disease, diagnosis, management, and prevention. Dermatol Ther 2010; 23: 458-76. pmid:20868401 PubMed  
  8. Medibas. Kondylom. Stokcholm; 2020. Sist revidert 02.11.20; sitert 04.02.21 medibas.se  
  9. Workowski KA, Berman S; Centers for Disease Control and Prevention (CDC). Sexually transmitted diseases treatment guidelines, 2010 published correction appears in MMWR Recomm Rep. 2011;60(1):18. MMWR Recomm Rep. 2010;59(RR-12):1–110.
  10. Mayeaux EJ Jr, Dunton C. Modern management of external genital warts. J Low Genit Tract Dis. 2008;12(3):185–192.
  11. Gotovtseva EP, Kapadia AS, Smolensky MH, Lairson DR. Optimal frequency of imiquimod (aldara) 5% cream for the treatment of external genital warts in immunocompetent adults: a meta-analysis. Sex Transm Dis 2008; 35: 346-51. pmid:18360317 PubMed  
  12. Grillo-Ardila CFAngel-Muller ESalazar-Diaz LC. Imiquimod for anogenital warts in non-immunocompromised adults. Cochrane Database Syst Rev. 2014 Nov 1;11:CD010389. Cochrane (DOI)  
  13. Ormerod AD, van Voorst Vader PC, Majewski S, et al. Evaluation of the efficacy, safety, and tolerability of 3 dose regimens of topical sodium nitrite with citric acid in patients with anogenital warts. JAMA Dermatol 2015. doi:10.1001/jamadermatol.2015.0381 DOI  
  14. Villa LL, Costa RLR, Petta CA, et al. Prophylactic quadrivalent human papillomavirus (types 6, 11, 16, and 18) L1 virus-like particle vaccine in young women: A randomised double-blind placebo-controlled multicentre phase II efficacy trial.. Lancet Oncol 2005; 6: 271-8. PubMed  
  15. Fairley CK, Hocking JS, Gurrin LC, et al. Rapid decline in presentations for genital warts after the implementation of a national quadrivalent human papillomavirus vaccination program for young women. Sex Transm Infect 2009; : PMID: 19837728. PubMed  
  16. Goodman MT, Shvetsov YB, McDuffie K, et al. Prevalence, acquisition and clearance of cervical human papillomavirus infection among women with normal cytology: Hawaii Human Papillimavirus cohort study. Cancer Res 2008; 68: 8813-24. PubMed  
  17. Shvetsov YB, Hernandez BY, McDuffie K, et al. Duration and clearance og anal human papillomavirus (HPV) infection among women: the Hawaii HPV cohort study. Clin Infect Dis 2009; 48: 547-9. PubMed  
  • Ingard Løge, spesialist allmennmedisin, redaktør NEL

Tidligere fagmedarbeidere

  • Per Bergsjø, professor emeritus, dr. med., Universitetet i Bergen. Spesialist i kvinnesykdommer og fødselshjelp, forsker ved Nasjonalt folkehelseinstitutt, Oslo