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Infertilitet

Sist revidert:
Sist revidert av:
Definisjon:
Manglende graviditet etter ett år med regelmessige og ubeskyttede samleier. 
Forekomst:
Infertilitet og subfertilitet oppleves av 9-15% av befolkningen i perioder eller vedvarende.
Symptomer:
Vanligvis ingen symptomer utover barnløsheten.
Funn:
Ofte normale kliniske funn både ved gynekologisk undersøkelse hos kvinnen og av testiklene hos mannen. Sjekk underliggende årsaker hos begge parter.
Diagnostikk:
Tilleggsundersøkelser vil være hormonprøver, sædundersøkelse og ultralyd.
Behandling:
Rettes først mot eventuelle underliggende årsaker, deretter eventuelt assistert befruktning.
  • Nasjonal behandlingstjeneste for assistert befruktning ved potensiell blodsmitte, Oslo Universitetssykehus, nettsted 
  • Hanevik HI et al. Infertilitet og fertilitetsbehandling. Norsk gynekologisk forening Veileder i gynekologi (2023). ePub. ISBN 978-82-692382-3-5. Hentet 25.09.2023
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  6. National Institute for Health and Care Excellence . Fertility: assessment and treatment for people with fertility problems. London: NICE; 2013. CG156. Last updated Sep 2017, visited May 2019 www.nice.org.uk  
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  9. Kimblad A, Ollvik G, Lindh CH, Axelsson J. Decreased sperm counts in Swedish users of oral tobacco. Andrology. 2022 Sep;10(6):1181-1188.Epub 2022 Jun 8. PMID: 35642735 PubMed  
  10. Skomsvoll JF, Rødevand E, Koksvik HS, et al. Reversibel infertilitet ved ikke-steroide antiinflammatoriske midler. Tidsskr Nor Lægeforen 2005; 125: 1476-8. pmid: 15940311 PubMed  
  11. Iliodromiti S, Kelsey TW, Wu O. The predictive accuracy of anti-Müllerian hormone for live birth after assisted conception: a systematic review and meta-analysis of the literature. Hum Reprod Update 2014; 20: 560-70. pmid:24532220 PubMed  
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  14. Eskew AM, Bedrick BS, Hardi A et al. Letrozole Compared With Clomiphene Citrate for Unexplained Infertility: A Systematic Review and Meta-analysis. Obstet Gynecol 2019; 133: 437-44. pmid:30741800 PubMed  
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  16. Chua SJ, Akande VA, Mol BWJ. Surgery for tubal infertility. Cochrane Database of Systematic Reviews 2017, Issue 1. Art. No.: CD006415. DOI: 10.1002/14651858.CD006415.pub3. DOI  
  17. Melo P, Georgiou EX, Johnson N, et al. Surgical treatment for tubal disease in women due to undergo in vitro fertilisation. Cochrane Database of Systematic Reviews 2020, Issue 10. Art. No.: CD002125. DOI: 10.1002/14651858.CD002125.pub4. DOI  
  18. Kroese ACJ, de Lange NM, Collins J, Evers JLH. Surgery or embolization for varicoceles in subfertile men. Cochrane Database of Systematic Reviews 2012, Issue 10. Art. No.: CD000479. DOI: 10.1002/14651858.CD000479.pub5 DOI  
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  • Eline Bragedatter Seljeflot, spesialist i Fødselshjelp og kvinnesykdommer, overlege ved Fertilitetsseksjonen ved St. Olavs hospital, Universitetssykehuset i Trondheim
  • Silje Folven Barlindhaug, spesialist i allmennmedisin, redaktør NEL