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Kardiomyopati, peripartum

Sist revidert:
Sist revidert av:


Definisjon:
Hjertesvikt med ejeksjonsfraksjon < 45% i siste svangerskapsmåned eller de første 6 måneder etter nedkomst hos kvinne uten kjent hjertesykdom. Årsaken er ukjent
Forekomst:
Sjelden tilstand
Symptomer:
Akutt eller langsomt innsettende hjertesvikt med tung pust, økte plager i liggende stilling, nattlig hoste
Funn:
Takykardi, væske i lunger, forstørret lever, ev. ødemer
Diagnostikk:
NT-proBNP forhøyet i blod. Diagnosen stilles ved ekkokardiografi
Behandling:
Behandling er som ved hjertesvikt av andre årsaker
  1. Sliwa K, Hilfiker-Kleiner D, Petrie MC, et al. Current state of knowledge on aetiology, diagnosis, management, and therapy of peripartum cardiomyopathy: a position statement from the Heart Failure Association of the European Society of Cardiology Working Group on peripartum cardiomyopathy. Eur J Heart Fail 2010; 12: 767. pmid:20675664 PubMed  
  2. Regitz-Zagrosek V, Roos-Hesselink JW, Bauersachs J, et al. 2018 ESC Guidelines for the management of cardiovascular diseases during pregnancy: The Task Force for the Management of Cardiovascular Diseases during Pregnancy of the European Society of Cardiology (ESC). Eur Heart J 2018; 39: 3165-3241. doi:10.1093/eurheartj/ehy340 DOI  
  3. Elliot P, Andersson B, Arbustini E, et al. Classification of the cardiomyopathies: a position statement from the european society of cardiology working group on myocardial and pericardial diseases. Eur Heart J 2008; 29: 270-6. European Heart Journal  
  4. Baris L, Cornette J, Johnson MR, et al. Peripartum cardiomyopathy: disease or syndrome?. Heart 2019; 105: 357-62. doi:10.1136/heartjnl-2018-314252 DOI  
  5. Norsk gynekologisk forening. Hjertesykdom og graviditet/fødsel. Veileder i fødselshjelp 2020. Siden lest 19.01.2022 www.legeforeningen.no  
  6. Ersbøll AS , Johansen M , Damm P , et al . Peripartum cardiomyopathy in Denmark: a retrospective, population-based study of incidence, management and outcome. Eur J Heart Fail 2017;19:1712–20. PMID: 28597481 PubMed  
  7. Kolte D, Khera S, Aronom WS, et al. Temporal trends in incidence and outcomes of peripartum cardiomyopathy in the United States: a nationwide population-based study. J Am Heart Assoc 2014; 3: E001056. pmid:24901108 PubMed  
  8. Sliwa K, Fett J, Elkayam U. Peripartum cardiomyopathy. Lancet 2006; 368: 687-93. PubMed  
  9. van Spaendonck-Zwarts KY, van Tintelen JP, van Veldhuisen DJ, et al. Peripartum cardiomyopathy as a part of familial dilated cardiomyopathy. Circulation 2010; 121: 2169. Circulation  
  10. Christiansen MN, Køber L, Torp-Pedersen C, et al. Prevalence of heart failure and other risk factors among first-degree relatives of women with peripartum cardiomyopathy. Heart 2019; 105: 1057-62. pmid:30910822 PubMed  
  11. van Spaendonck-Zwarts KY , Posafalvi A , van den Berg MP , et al . Titin gene mutations are common in families with both peripartum cardiomyopathy and dilated cardiomyopathy. Eur Heart J 2014;35:2165–73. PMID: 24558114 PubMed  
  12. Pearson GD, Veille JC, Rahimtoola S, et al. Peripartum cardiomyopathy. National Heart, Lung, and Blood Institute and Office of Rare Diseases (National Institutes of Health) Workshop recommendations and review. JAMA 2000; 283: 1183-8. Journal of the American Medical Association  
  13. Sliwa K, Forster O, Libhaber E et al. Peripartum cardiomyopathy: inflammatory markers as predictors of outcome in 100 prospectively studied patients. Eur Heart J 2006; 27: 441-6. European Heart Journal  
  14. Fett JD, Carraway RD, Dowell DL, King ME and Pierre R. Periptum cardiomyopathy in the Hospital Albert Schweitzer District of Haiti. Am J Obstet Gynecol 2002; 186: 1005-10. PubMed  
  15. Elkayam U, Akhter MW, Singh HS, et al. Pregnancy-associated cardiomyopathy: clinical characteristics and a comparison between early and late presentation. Circulation 2005; 111: 2050-5. Circulation  
  16. Bauersachs J, Arrigo M, Hilfiker-Kleiner D, et al. Current management of patients with severe acute peripartum cardiomyopathy: practical guidance from the Heart Failure Association of the European Society of Cardiology Study Group on peripartum cardiomyopathy. Eur Heart J Fail 2016; 9: 1096-105. pmid:27338866 PubMed  
  17. Phillips SD and Warnes CA. Peripartum cardiomyopathy: current therapeutic perspectives. Curr Treat Options Cardiovasc Med 2004; 6: 481-8. PubMed  
  18. Mallikethi-Reddy S, Akintoye E, Trehan N, et al. Burden of arrhythmias in peripartum cardiomyopathy: Analysis of 9841 hospitalizations. Int J Cardiol 2017; 235: 114. pmid:28268089 PubMed  
  19. Hilfiker-Kleiner D, Haghikia A, Masuko D, et al. Outcome of subsequent pregnancies in patients with a history of peripartum cardiomyopathy. Eur J Heart Fail 2017;19:1723–1728. PMID: 28345302 PubMed  
  • Ingard Løge, spesialist allmennmedisin, redaktør Norsk Elektronisk Legehåndbok (NEL)