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Helvetesild, herpes zoster

Helvetesild gir ubehag og smerter som kløe, prikking og svie. Utslettet kan bryte ut samtidig med smertene, eller komme etterpå. Personer med helvetesild kan smitte andre med vannkopper.

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Den ligger åpent tilgjengelig på NHI.no sammen annen relevant informasjon

https://nhi.no/sykdommer/hud/smablarete-utslett/helvetesild/ 

Hva er helvetesild?

Årsaker til helvetesild

Diagnostikk av helvetesild

Behandling av helvetesild

Vaksinering

Er det smittefare ved helvetesild?

Prognose ved helvetesild

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Quiz

Illustrasjoner

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Referanser

Dette dokumentet er basert på det profesjonelle dokumentet Herpes zoster. Referanselisten for dette dokumentet vises nedenfor.

  1. Kofoed K, Rønholt F, Gerstoft J, Sand C. Herpes zoster: klinik, diagnostik og behandling. Ugeskr Læger 2011; 173: 114. Ugeskrift for Læger 
  2. Saguil A, Kane S, Mercado M, Lauters R. Herpes zoster and postherpetic neuralgia: Prevention and management. Am Fam Physician 2017 Nov 15;96(10):656-663. Pmid: 29431387 PubMed 
  3. Fashner J, Bell AL. Herpes zoster and postherpetic neuralgia: prevention and management. Am Fam Physician 2011; 83: 1432-7. American Family Physician 
  4. Johnson BH, Palmer L, Gatwood J, et al. Annual incidence rates of herpes zoster among an immunocompetent population in the United States. BMC Infect Dis. 2015;15:502. PubMed 
  5. Gnann JW, Whitley RJ. Herpes zoster. N Engl J Med 2002; 347: 340-6. PubMed 
  6. Oxman MN, Levin MJ, Johnson GR, et al. A vaccine to prevent herpes zoster and postherpetic neuralgia in older adults. N Engl J Med 2005; 352: 2271-84. New England Journal of Medicine 
  7. Wang Y-P, Liu C-J, Hu Y-W, et al. Risk of cancer among patients with herpes zoster infection: a population-based study. CMAJ 2012. doi:10.1503/CMAJ.120518 DOI 
  8. Gebo KA, Kalyani R, Moore RD, Polydefkis MJ. The incidence of, risk factors for, and sequelae of herpes zoster among HIV patients in the highly active antiretroviral therapy era. J Acquir Immune Defic Syndr 2005; 40: 169. PubMed 
  9. Forbes HJ, Bhaskaran K, Thomas SL, et al. Quantification of risk factors for herpes zoster: population based case-control study. BMJ 2014; 348: g2911. BMJ (DOI) 
  10. Wang YP, Liu CJ, Hu YW, et al. Risk of cancer among patients with herpes zoster infection: a population-based study. CMAJ 2012 Oct 16; 184(15): E804-9. PMID: 22988158. PubMed 
  11. Dworkin RH, Johnson RW, Breuer J, et al. Recommendations for the management of herpes zoster. Clin Infect Dis 2007; 44 Suppl 1: S1.
  12. Helgason S, Petursson G, Gudmundsson S, Sigurdsson JA. Prevalence of post-herpetic neuralgia after a first episode of herpes zoster: a prospective study with long term follow up. BMJ 2000; 321: 794-6. PubMed 
  13. Jumaan AO, Yu O, Jackson LA, et al. Incidence of herpes zoster, before and after varicella-vaccination-associated decreases in the incidence of varicella, 1992-2002. J Infect Dis 2005; 191: 2002. PubMed 
  14. Yawn BP, Saddier P, Wollan PC, et al. A population-based study of the incidence and complication rates of herpes zoster before zoster vaccine introduction. Mayo Clin Proc 2007; 82: 1341. PubMed 
  15. Albrecht MA. Epidemiology, clinical manifestations, and diagnosis of herpes zoster. UpToDate, last updated Jun 20, 2022. www.uptodate.com 
  16. Albrecht MA. Treatment of herpes zoster in the immunocompetent host. UpToDate, last updated Mar 11, 2020. Siden lest 30.3.2023. www.uptodate.com 
  17. John AR, Canaday DH. Herpes Zoster in the Older Adult. Infect Dis Clin North Am. 2017;31(4):811-826. PMID: 29079160 PubMed 
  18. Chen N, Li Q, Yang J, et al. Antiviral treatment for preventing postherpetic neuralgia. Cochrane Database Syst Rev. 2014;2:CD006866. PMID: 24500927 pubmed.ncbi.nlm.nih.gov 
  19. Pasternak B, Hviid A. Use of acyclovir, valacyklovir, and famciclovir in the first trimester of pregnancy and the risk of birth defects. JAMA 2010; 304: 859-66. Journal of the American Medical Association 
  20. Statens legemiddelverk. Riktigere bruk av NSAIDs. Terapiråd til helsepersonell, utarbeidet i samarbeid med RELIS. Publisert 21.09.2016. Siden lest 30.03.2023. legemiddelverket.no 
  21. Han Y, Zhang J, Chen N, He L, Zhou M, Zhu C. Corticosteroids for preventing postherpetic neuralgia. Cochrane Database of Systematic Reviews 2013, Issue 3. Art. No.: CD005582. DOI: 10.1002/14651858.CD005582.pub4. DOI 
  22. Colin J, Prisant O, Cochener B, Lescale O, Rolland B, Hoang-Xuan T. Comparison of the efficacy and safety of valaciclovir and acyclovir for the treatment of herpes zoster ophthalmicus. Br J Ophthalmol 2000; 107: 1507-11. PubMed 
  23. Alper BS, Lewis PR. Does treatment of Acute Herpes Zoster Prevent or Shorten Postherpetic Neuralgia? A Systematic Review of the Literature. J Fam Pract 2000, 49;3:255-64.
  24. Gagliardi AMZ, Andriolo BNG, Torloni MR, Soares BGO, de Oliveira Gomes J, Andriolo RB, Canteiro Cruz E. Vaccines for preventing herpes zoster in older adults. Cochrane Database of Systematic Reviews 2019, Issue 11. Art. No.: CD008858. DOI: 10.1002/14651858.CD008858.pub4. Accessed 10 May 2022 The Cochrane Library 
  25. Forbes H, Douglas I, Finn A, et al. Risk of herpes zoster after exposure to varicella to explore the exogenous boosting hypothesis: self controlled case series study using UK electronic healthcare data. BMJ 2020; 368: l6987. pmid:31969318 PubMed 
  26. Weinmann S, Chun C, Schmid DS, et al. Incidence and clinical characteristics of herpes zoster among children in the varicella vaccine era, 2005-2009. J Infect Dis 2013; 208: 1859-68. doi:10.1093/infdis/jit405
  27. Breuer J, Pacoud M, Gauthier A, Brown MM. Herps zoster as a risk factor for stroke and TIA. Neurology 2014. doi:10.1212/WNL.0000000000000038 DOI 
  28. Insinga RP, Itzler RF, Pellissier JM, et al. The incidence of herpes zoster in a United States administrative database. J Gen Intern Med 2005; 20: 748-53. PubMed 
  29. Berry JD, Petersen KL. A single dose of gabapentin reduces acute pain and allodynia in patients with herpes zoster. Neurology 2005; 65: 444-7. Neurology 
  30. Thyregod HG, Rowbotham MC, Peters M, Possehn J, Berro M, Petersen KL. Natural history of pain following herpes zoster. Pain 2007; 128: 148-156. PubMed 
  31. Wood MJ, Shukla S, FIddian AP, Crooks RJ. Treatment of acute herpes zoster: effect of early (< 48 h) versus late (48-72 h) therapy with acyclovir and valaciclovir on prolonged pain. J Infect Dis 1998; 178 (Suppl 1): S81-S84.
  32. Kofoed K, Rønholt F, Gerstoft J, Sand C. Forebyggelse af herpes zoster med vaccination. Ugeskr Læger 2011; 173: 110. Ugeskrift for Læger 
  33. Chen N, Li Q, Zhang Y, et al. Vaccination for preventing postherpetic neuralgia. Cochrane Database of Systematic Reviews 2011; 3: CD007795. doi:10.1002/14651858.CD007795.pub2 DOI 
  34. Morrison VA, Johnson GR, Schmader KE. Long-term persistence of zoster vaccine efficacy. Clin Infect Dis 2015; 60:900 DOI: 10.1093/cid/ciu918
  35. Zhang J, Xie F, Delzell E, et al. Association between vaccination for herps zoster and risk of herpes zoster infection among older patients with selected immune-mediated diseases. JAMA 2012; 308: 43-9. Journal of the American Medical Association 
  36. Tseng HF, Chi M, Smith N, et al. Herpes zoster vaccine and the incidence of recurrent herpes zoster in an immunocompetent elderly population. J Infect Dis 2012; 206: 190-6. PubMed 
  37. Simberkoff MS, Arbeit RD, Johnson GR, et al. Safety of herpes zoster vaccine in the Shingles Prevention Study: A randomized trial. Ann Intern Med 2010; 152: 545-54. Annals of Internal Medicine 
  38. Kawai K, Preaud E, Baron-Papillon F, et al. Cost-effectiveness of vaccination against herpes zoster and postherpetic neuralgia: a critical review. Vaccine. 2014 ;32(15):1645-53. doi: 10.1016/j.vaccine.2014.01.058 DOI