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Pemfigoid

Sist oppdatert: Sist revidert:
Sist revidert av:
Definisjon:
Bulløs pemfigoid er en autoimmun og relativt benign sykdom med spente subepidermale bullae på erytematøs eller normalt utseende hud
Forekomst:
Insidens er funnet å være 4,3 per 100.000 personår. Rammer særlig eldre personer
Symptomer:
Debuterer gjerne med sterkt kløende, urtikarialiknende eksantem og etter hvert danning av store, spente blemmer
Funn:
Kliniske funn er opptil flere cm store halvkuleformede spente blærer som er utbredt over huden. Ca 1/3 har slimhinnelesjoner
Diagnostikk:
Aktuelle tilleggsundersøkelser er autoantistoffer, ev. histologi
Behandling:
Vanligvis systemiske steroider, noen ganger immundempende midler, ev. tetrasyklin, ev. lokale steroider
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  • Terje Johannessen, professor i allmennmedisin, Trondheim
  • Morten Dalaker, avtalespesialist i hudsykdommer, Trondheim Hudlegesenter, Carl Johans gt 3, 7010 Trondheim