Acanthosis nigricans
Publisert:
Sist revidert av:Terje Johannessen
Definisjon:
Hudsykdom med hyperpigmenterte områder på intertriginøse steder. Skyldes underliggende metabolske forstyrrelser, ev. arv. Kan føre til malign tilstand
Forekomst:
Økt prevalens blant ikke-hvite og ikke-asiatiske. Hyppigst blant personer under 40 år
Symptomer:
Fløyelsmyke, hyperpigmenterte plakk på huden oftest på nakken, i aksillene, i lysken. Betydelig kløe kan tyde på underliggende kreftsykdom
Funn:
Typisk foreligger intertriginøs hyperpigmentering, etter hvert verrucøse eller plakkliknende palpable forandringer
Diagnostikk:
Klinisk diagnose, ev. histologi
Behandling:
Eliminering av underliggende sykdom
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- Terje Johannessen, professor i allmennmedisin, Trondheim