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Acanthosis nigricans

Publisert:
Sist revidert av:
Definisjon:
Hudsykdom med hyperpigmenterte områder på intertriginøse steder. Skyldes underliggende metabolske forstyrrelser, ev. arv. Kan føre til malign tilstand
Forekomst:
Økt prevalens blant ikke-hvite og ikke-asiatiske. Hyppigst blant personer under 40 år
Symptomer:
Fløyelsmyke, hyperpigmenterte plakk på huden oftest på nakken, i aksillene, i lysken. Betydelig kløe kan tyde på underliggende kreftsykdom
Funn:
Typisk foreligger intertriginøs hyperpigmentering, etter hvert verrucøse eller plakkliknende palpable forandringer
Diagnostikk:
Klinisk diagnose, ev. histologi
Behandling:
Eliminering av underliggende sykdom
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  9. Wang L, Long H, Wen H, et al. Image Gallery: Generalized mucosal and cutaneous papillomatosis, a unique sign of malignant acanthosis nigricans. Br J Dermatol 2017; 176:e99. PubMed  
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  • Terje Johannessen, professor i allmennmedisin, Trondheim