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Akne

Sist oppdatert: Sist revidert:
Sist revidert av:


Definisjon:
Kronisk inflammatorisk sykdom i taglkjertelapparatet i ansikt og på øvre del av truncus
Forekomst:
25-85% av ungdom og yngre voksne i alderen 11-30 år opplever akneelementer
Symptomer:
Utbrudd lokalisert til ansikt, hals, øvre del av brystet, rygg og skuldre
Funn:
Komedoner, pustler, inflammatoriske papulopustler, ev. smertefulle noduli, cyster, arr
Diagnostikk:
Tilleggsundersøkelser er vanligvis ikke påkrevd
Behandling:
Kombinasjon av ulike lokale (benzoylperoksid, retinoid, azelain) ev. systemiske midler (antibiotika, isotretinoin)
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  2. Helsedirektoratet (2021). Nasjonal faglig retningslinje for antibiotika i primærhelsetjenesten nettdokument. Oslo: Helsedirektoratet (sist faglig oppdatert 16. november 2021, lest jan 2022).
  3. Stangeland KZ, Huldt-Nystrøm T, Li X, Danielsen K. Behandling av akne. Tidsskr Nor Legeforen 2019. doi:10.4045/tidsskr.18.0946 DOI  
  4. Mahmood NF, Shipman AR. The age-old problem of acne. Int J Womens Dermatol 2017 ; 3(2): 71-76. pmid:28560299 PubMed  
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  6. Cunliffe WJ, Holland DB, Clark SM et al. Comedogenesis: some new aethiological, clinical and therapeutic strategies. Br J Dermatol 2000; 142; 1084-91.
  7. Mikkelsen CS, Hansen SR, Kroon S. Lokalbehandling av akne. Tidsskr Nor Legeforen 2011; 131: 33-4. DOI: 10.4045/tidsskr.09.1312 tidsskriftet.no  
  8. Thiboutot D, Zaenglein A. Pathogenesis, clinical manifestations, and diagnosis of acne vulgaris. UpToDate, last updated Nov 12, 2019. www.uptodate.com  
  9. Bowe WP, Joshi SS, Shalita AR. Diet and acne. J Am Acad Dermatol 2010; 63: 124-41. PubMed  
  10. Meixiong J, Ricco C, Vasavda C, Ho BK. Diet and acne: A systematic review. JAAD Int. 2022 Mar 29;7:95-112. PMID: 35373155 PubMed  
  11. Maroñas-Jiménez L, Krakowski AC. Pediatric Acne: Clinical Patterns and Pearls. Dermatol Clin. 2016 Apr;34(2):195-202. PMID: 27015779. PubMed  
  12. Hansen SR, Mikkelsen CS, Kroon S. Systemisk behandling av akne. Tidsskr Nor Legeforen 2011; 131: 133-4. Tidsskrift for Den norske legeforening  
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  16. Dall'Oglio F, Nasca MR, Fiorentini F, Micali G. Diet and acne: review of the evidence from 2009 to 2020. Int J Dermatol. 2021 Jan 18. doi: 10.1111/ijd.15390. Epub ahead of print. PMID: 33462816.Dall'Oglio F, Nasca MR, Fiorentini F, Micali G. Diet and acne: review of the evidence from 2009 to 2020. Int J Dermatol. 2021 Jan 18. Epub ahead of print. PMID: 33462816. PubMed  
  17. RELIS. Kilde: Bandlien CL, Roland PD. Acne vulgaris, behandling med lokale og systemiske aknemidler. Nor Farmaceut Tidsskr 2016; 124(6): 28-31. Publisert 21.06.2016. Siden besøkt 21.06.2021. relis.no  
  18. RELIS. Behandling av akne ved amming. RELIS database 2018; spm.nr. 6977, RELIS Midt-Norge. Siden besøkt 01.04.2020. relis.no  
  19. Yang Z, Zhang Y, Lazic Mosler E, et al. Topical benzoyl peroxide for acne. Cochrane Database Syst Rev. 2020 Mar 16;3:CD011154. (Systematic review). Pmid: 32175593 PubMed  
  20. Arowojolu AO, Gallo MF, Lopez LM, Grimes DA. Combined oral contraceptive pills for treatment of acne. Cochrane Database of Systematic Reviews 2012, Issue 7. Art. No.: CD004425. DOI: 10.1002/14651858.CD004425.pub6 DOI  
  21. Zaenglein AL, Pathy AL, Schlosser BJ, Alikhan A et al. Guidelines of care for the management of acne vulgaris. J Am Acad Dermatol. 2016 May;74(5):945-73.e33. doi: 10.1016/j.jaad.2015.12.037. Epub 2016 Feb 17. Erratum in: J Am Acad Dermatol. 2020 Jun;82(6):1576. PMID: 26897386 PubMed  
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  25. Costa CS, Bagatin E, Martimbianco ALC. Oral isotretinoin for acne. Cochrane Database of Systematic Reviews 2018, Issue 11. Art. No.: CD009435. DOI: 10.1002/14651858.CD009435.pub2. DOI  
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  29. Dall'oglio F, Puglisi DF, Nasca MR, Micali G. Acne fulminans. G Ital Dermatol Venereol. 2020 Dec;155(6):711-718. Epub 2020 Oct 21. PMID: 33084268 PubMed  
  30. Barbaric J, Abbott R, Posadzki P, et al.. Light therapies for acne. Cochrane Database Syst Rev. 2016. pmid:27670126 PubMed  
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  32. Gollnick H, Cunliffe W, Berson D et al; Global Alliance to Improve Outcomes in Acne. Management of acne: a report from a Global Alliance to Improve Outcomes in Acne. J Am Acad Dermatol 2003; 49 (suppl): S1-37.
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  • Peter D. Jost, spesialist i allmennmedisin, redaktør NEL, Trondheim

Tidligere fagmedarbeidere

  • Sylvi Torvund, spesialist i allmennmedisin, Nidarvold legesenter, Trondheim
  • Ole Fyrand, overlege og professor, Hudavdelingen, Rikshospitalet og Universitetet i Oslo