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Sarkoidose

Sist oppdatert: Sist revidert:
Sist revidert av:
Definisjon:
Idiopatisk, granulomatøs systemsykdom som oftest affiserer lunger og intratorakale lymfeknuter, men også ekstratorakale manifestasjoner er hyppige
Forekomst:
Usikre tall, tilstanden er ofte asymptomatisk. Insidens er 5-18 per 100000 per år. Debuterer hyppigst i aldersgruppen 30-55 år 
Symptomer:
30-50% er symptomfrie og oppdages ved et tilfeldig rtg. thorax. Symptomatisk sykdom debuterer enten akutt eller smygende. Hoste, tungpusthet, diffuse brystsmerter, ev. slitenhet og sykdomsfølelse
Funn:
Alle organer kan affiseres, men hyppigst lunger, hud, lymfeknuter, lever. Som regel få eller ingen organiske funn
Diagnostikk:
Finnes ingen definitiv diagnostisk test. Røntgen, ev. CT, blodprøver, histologi
Behandling:
Selvhelbredende hos en god del pasienter. Ved progressiv sykdom behandles med kortikosteroider, ev. immunsupprimerende eller biologiske medisiner, ev. transplantasjon
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  • Peter Jost, spesialist i allmennmedisin, redaktør NEL, Trondheim
  • Terje Johannessen, professor i allmennmedisin, Trondheim

Tidligere fagmedarbeidere

  • Hasse Melbye, spesialist i allmennmedisin, førsteamanuensis ved institutt for samfunnsmedisin, Universitetet i Tromsø
  • Helge Bjørnstad Pettersen, overlege/førsteamanuensis, Lungeavdelingen, Regionsykehuset i Trondheim og Norges Teknisk Naturvitenskapelige Universitet, Trondheim