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En firedel av sårene i magesekken skyldes skader fra bruk av NSAIDs eller salicylater.
En firedel av sårene i magesekken skyldes skader fra bruk av NSAIDs eller salicylater.

Magesår forårsaket av NSAIDs

Pasienter som skal bruke NSAIDs, blir advart mot at slik medisin kan forårsake mageplager.

Sist revidert:
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Del pasientinformasjon

Den ligger åpent tilgjengelig på NHI.no sammen annen relevant informasjon

https://nhi.no/sykdommer/magetarm/magesekk/magesar-forarsaket-av-nsaids/ 

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Referanser

Dette dokumentet er basert på det profesjonelle dokumentet Magesår. Referanselisten for dette dokumentet vises nedenfor.

  1. Fashner J, Gitu AC. Diagnosis and treatment of peptic ulcer disease and H. pylori infection. Am Fam Physician 2015; 91(4): 236-242. www.aafp.org 
  2. Lanas A, Chand FKL. Peptic ulcer disease. Lancet 2017; 390: 613–24. doi:10.1016/ S0140-6736(16)32404-7
  3. Ford AC, Marwaha A, Lim A, Moayyedi P. What is the prevalence of clinically significant endoscopic findings in subjects with dyspepsia? Systematic review and meta-analysis. Clin Gastroenterol Hepatol. 2010;8(10):830-837.e8372. PMID: 20541625 PubMed 
  4. Vakil NB. Peptic ulcer disease: Epidemiology, etiology, and pathogenesis. UpToDate, last updated Mar 02, 2020. UpToDate 
  5. Moayyedi P, Lacy BE, Andrews CN, Enns RA, Howden CW, Vakil N. ACG and CAG Clinical Guideline: Management of Dyspepsia. Am J Gastroenterol. 2017;112(7):988-1013. PubMed 
  6. Lee Lynch K. Peptic ulcer disease. BMJ Best Practice, last updated 10 Sep 2020. bestpractice.bmj.com 
  7. Saeed M, Bass S, Chaisson NF. Which ICU patients need stress ulcer prophylaxis?. Cleve Clin J Med. 2022;89(7):363-367. Published 2022 Jul 1. PMID: 35777844 PubMed 
  8. Kavitt RT, Lipowska AM, Anyane-Yeboa A, Gralnek IM. Diagnosis and Treatment of Peptic Ulcer Disease. Am J Med. 2019;132(4):447-456. PubMed 
  9. Anand BS. Peptic ulcer disease. Medscape, last updated Oct 03, 2018. emedicine.medscape.com 
  10. Nasjonale retningslinjer: Antibiotika i sykehus. Helicobacter pylori infeksjon. Helsedirektoratet. Sist faglig oppdatert 01.mars 2022. www.helsedirektoratet.no 
  11. Tielleman T, Bujanda D, Cryer B. Epidemiology and Risk Factors for Upper Gastrointestinal Bleeding. Gastrointest Endosc Clin N Am. 2015;25(3):415-428. PubMed 
  12. Schmidt M, Riis AH, Christiansen CF, Lash TL, Sørensen HT. Clopidogrel use and short-term mortality after peptic ulcer bleeding: a population-based cohort study. Am J Ther. 2013;20(1):13-20. PubMed 
  13. Helsedirektoratet. Nasjonal faglig retningslinje for antibiotika i primærhelsetjenesten. Dyspepsi og Helicobacter pylori-infeksjon. Sist faglig oppdatert: 16. november 2021. www.helsedirektoratet.no 
  14. Best LM, Takwoingi Y, Siddique S, et al. Non-invasive diagnostic tests for Helicobacter pylori infection. Cochrane Database Syst Rev. 2018 Mar 15;(3):CD012080. Cochrane (DOI) 
  15. Lamont JT. Indications and diagnostic tests for Helicobacter pylori infection in adults. UpToDate, last updated May 02, 2022. UpToDate 
  16. Chey WD, Leontiadis GI, Howden CW, et al. ACG clinical guideline: treatment of Helicobacter pylori infection. Am J Gastroenterol. 2017;112:212-239. PubMed 
  17. Ford AC, Gurusamy KS, Delaney B, et al. Eradication therapy for peptic ulcer disease in Helicobacter pylori-positive people. Cochrane Database Syst Rev. 2016;(4):CD003840. Cochrane (DOI) 
  18. Yuan Y, Ford AC, Khan KJ, et al. Optimum duration of regimens for Helicobacter pylori eradication. Cochrane Database Syst Rev 2013 Dec 11;12:CD008337. Cochrane (DOI) 
  19. Szajewska H, Horvath A, Piwowarczyk A. Meta-analysis: the effects of Saccharomyces boulardii supplementation on Helicobacter pylori eradication rates and side effects during treatment. Aliment Pharmacol Ther 2010; 32: 1060-79. PubMed 
  20. Zhao Y, Li Y, Hu J, et al. The Effect of Helicobacter pylori Eradication in Patients with Gastroesophageal Reflux Disease: A Meta-Analysis of Randomized Controlled Studies. Dig Dis. 2020;38(4):261-268. PMID: 32396919.
  21. Grove EL, Würtz M, Schwarz P, Jørgensen NR, Vestergaard P. Gastrointestinal events with clopidogrel: a nationwide population-based cohort study. J Gen Intern Med. 2013;28(2):216-222. PubMed 
  22. Sanabria A, Villegas MI, Morales Uribe CH. Laparoscopic repair for perforated peptic ulcer disease. Cochrane Database of Systematic Reviews 2013, Issue 2. Art. No.: CD004778. DOI: 10.1002/14651858.CD004778.pub3 DOI 
  23. Zeng M, Mao X-H, Li J-X, et al. Efficacy, safety, and immunogenicity of an oral recombinant Helicobacter pylori vaccine in children in China: A randomised, double-blind, placebo-controlled, phase 3 trial. Lancet 2015. doi: 10.1016/S0140-6736(15)60579-7 DOI 
  24. Barkun AN, Bardou M, Kuipers EJ, et al. International consensus recommendations on the management of patients with nonvariceal upper gastrointestinal bleeding. Ann Intern Med 2010; 152: 101-13. PubMed 
  25. Würtz M, Grove EL, Kristensen SD, Hvas A-M. The antiplatelet effect of aspirin is reduced by proton pump inhibitors in patients with coronary artery disease. Heart 2009; e-pub: PMID:19910291. PubMed 
  26. Niv Y. H pylori recurrence after successful eradication. World J Gastroenterol. 2008 Mar 14;14(10):1477-8. PMID: 18330934. PubMed 
  27. Lau JY, Sung J, Hill C, et al. Systematic review of the epidemiology of complicated peptic ulcer disease: incidence, recurrence, risk factors and mortality. Digestion 2011; 84:102. PubMed 
  28. Forsmo HM, Vandvik PO, Glomsaker T. Ulcus perforatum - et 12-årsmateriale. Tidsskr Nor Lægeforen 2005; 125: 1822-4. Tidsskrift for Den norske legeforening