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Hepatocellulært karsinom

Sist oppdatert: Sist revidert:
Sist revidert av:
Definisjon:
Er en primær leverkreftsykdom som utgår fra hepatocytter, vanligvis i forløpet av en kronisk leversykdom, særlig virushepatitt
Forekomst:
Lav forekomst i Norge fordi insidensen av hepatitt er lav
Symptomer:
Pasientene har som regel symptomer fra den underliggende kroniske leversykdommen og man blir oppmerksom på tilstanden ved rask forverring
Funn:
Tegn på den tilgrunnliggende sykdommen, cirrhose/leversvikt, forekommer i form av spenomegali, ascites, ikterus, spider nevi, gynekomasti
Diagnostikk:
Tilleggsundersøkelser viser forhøyet ALAT, ALP, GT, bilirubin og lav NT, albumin, trombocytter, ev. alfaføtoprotein. Bildediagnostikk + biopsi
Behandling:
Kirurgisk fjerning av svulster, leverreseksjon, er vanligvis nytteløst dersom cirrhose er tilstede og svulsten er stor eller multifokal. Ev. levertransplantasjon
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  • Terje Johannessen, professor i allmennmedisin, Trondheim

Tidligere fagmedarbeidere

  • Lars Aabakken, førsteamanuensis ved Universitetet i Oslo, lege ved Medisinsk avdeling, Rikshospitalet