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Leverencefalopati

Sist revidert:
Sist revidert av:

Definisjon:
Leverencefalopati er nevropsykiatriske symptomer som oppstår ved leversykdom med portosystemisk shunting, det vil si ved levercirrhose og ved akutte leverskader. Endringene i hjernefunksjon skyldes metabolske forandringer
Forekomst:
Sjelden tilstand, men ikke uvanlig ved levercirrhose
Symptomer:
Personlighetsforandringer, intellektuelle forstyrrelser, nedsatt bevissthetsnivå og koma
Funn:
Foetor hepaticus, tremor, bradykinesi, hyperaktive senereflekser, ev. tegn på kronisk leversykdom
Diagnostikk:
Forhøyet ammonium, leverfunksjonsprøver viser betydelig nedsatt funksjon, EEG viser karakteristiske funn
Behandling:
Rettes mot utløsende årsaker og reduksjon av ammonium
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  • Terje Johannessen, professor i allmennmedisin, Trondheim

Tidligere fagmedarbeidere

  • Espen Dietrichs, professor og avdelingsoverlege, Universitetet i Oslo og Nevrologisk avdeling, Rikshospitalet, Oslo