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Dieulafoy lesjon

Sist revidert:
Sist revidert av:


Definisjon:
Residiverende, intermitterende og livstruende blødninger i magetarmkanalen som skyldes ruptur av en ueksponert submukøs arterie
Forekomst:
Sjelden tilstand
Symptomer:
Residiverende episoder med hematemese og/eller melena
Funn:
I akuttfasen kan det foreligge hemodynamisk instabilitet, postural hypotensjon og markant anemi
Diagnostikk:
Hb, Htc, endoskopi
Behandling:
Endoskopisk behandling
  1. Inayat F, Amjad W, Hussain Q, Hurairah A. Dieulafoy's lesion of the duodenum: a comparative review of 37 cases. BMJ Case Rep. 2018;2018:bcr2017223246. Published 2018 Feb 22. PMID: 29472423 PubMed  
  2. Lara LF, Sreenarasimhaiah J, Tang SJ, et al. Dieulafoy lesions of the GI tract: localization and therapeutic outcomes. Dig Dis Sci 2010; 55:3436. PubMed  
  3. De Palma GD, Patrone F, Rega M, Simeoli I, Masone S, Persico G. Actively bleeding Dieulafoy's lesion of the small bowel identified by capsula endoscopy and treated by push enteroscopy. World J Gastroenterol 2006; 12: 3936-7. PubMed  
  4. Rockey DC. Causes of upper gastrointestinal bleeding in adults. UpToDate, last updated Jul 27, 2020. UpToDate  
  5. Batouli A, Kazemi A, Hartman MS, Heller MT, Midian R, Lupetin AR. Dieulafoy lesion: CT diagnosis of this lesser-known cause of gastrointestinal bleeding. Clin Radiol. 2015;70(6):661-666. PubMed  
  6. Kolli S, Dang-Ho KP, Mori A, Gurram K. The Baader-Meinhof Phenomenon of Dieulafoy's Lesion. Cureus. 2019;11(5):e4595. Published 2019 May 3. PMID: 31309020 PubMed  
  7. Neu B, Ell C, May A, Schmid E, Riemann JF, Hagenmüller F, et al. Capsule endoscopy versus standard tests in influencing management of obscure digestive bleeding: results from a German multicenter trial. Am J Gastroenterol 2005; 100: 1736-42. PubMed  
  8. Patel P, Tobi M. Dieulafoy-like lesion bleeding: in the loop. Gastroenterol Hepatol (N Y). 2011;7(4):271-274. PubMed  
  9. Streicher HJ. Solitary exulceratio simplex (Dieulafoy) as cause of massive intestinal hemorrhage. Dtsch Med Wochenschr 1966; 91: 991-5. PubMed  
  • Terje Johannessen, professor i allmennmedisin, Trondheim

Tidligere fagmedarbeidere

  • Lars Aabakken, dr. med, seksjonsoverlege ved Medisinsk avdeling, Rikshospitalet