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Spiserørskreft

Sist oppdatert: Sist revidert:
Sist revidert av:

Definisjon:
Malign svulst i øsofagus. Epiteliale svulster (95%) - 1/5 er plateepitelkarsinom og 4/5 adenokarsinom
Forekomst:
Utgjør 1% av alle krefttilfeller
Symptomer:
Dysfagi er det vanligste symptomet, dernest vekttap og smerter
Funn:
Ingen spesifikke kliniske funn, men avmagring og svekket allmenntilstand foreligger ofte på grunn av spredning
Diagnostikk:
Diagnosen stilles ved histologisk bedømmelse av biopsi tatt ved endoskopi
Behandling:
Kirurgi er eneste behandling med mulighet for langtidsoverlevelse
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  10. Tramacere I, La Vecchia C, Negri E. Tobacco smoking and esophageal and gastric cardia adenocarcinoma: a meta-analysis. Epidemiology. 2011;22(3):344–349.
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  16. Stapley S, Peters TJ, Neal RD et al. The risk of oesophago-gastric cancer in symptomatic patients in primary care: a large case-control study using electronic records. Br J Cancer. 2013;108:25-31. PMID: 23257895. PubMed  
  17. Bartley AN, Washington MK, Colasacco C et al. HER2 Testing and Clinical Decision Making in Gastroesophageal Adenocarcinoma: Guideline From the College of American Pathologists, American Society for Clinical Pathology, and the American Society of Clinical Oncology. J Clin Oncol 2017; 35(4): 446-64. pmid:28129524 PubMed  
  18. Krasna MJ. Oesophageal cancer. BMJ Best Practice, last updated Jan 27, 2015.
  19. Sjoquist KM, Burmeister BH, Smithers BM et al. Survival after neoadjuvant chemotherapy or chemoradiotherapy for resectable oesophageal carcinoma: an updated meta-analysis. Lancet Oncol 2011; 12: 681-92. pmid:21684205 PubMed  
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  • Silje Folven Barlindhaug, spesialist i allmennmedisin, redaksjonsmedarbeider NEL
  • Terje Johannessen, professor i allmennmedisin, Trondheim

Tidligere fagmedarbeidere

  • Ingebjørg S. Juel, assistentlege, Kirurgisk klinikk, St. Olavs Hospital
  • Jon Erik Grønbech, professor og overlege, Norges teknisk-naturvitenskapelige universitet og Kirurgisk avdeling, Regionsykehuset i Trondheim