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Akutt disseminert encefalomyelitt (ADEM)

ADEM er en tilstand karakterisert ved betennelse og skade på myelinskjeder i hjernen og ryggmargen.

Sist revidert:

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Del pasientinformasjon

Den ligger åpent tilgjengelig på NHI.no sammen annen relevant informasjon

https://nhi.no/sykdommer/barn/nervesystemet/akutt-disseminert-encefalomyelitt-adem/ 

Hva er akutt disseminert encefalomyelitt?

Risikogrupper

Årsaker til ADEM

Symptomer

Diagnostikk

Behandling

Prognose

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Referanser

Dette dokumentet er basert på det profesjonelle dokumentet Akutt disseminert encefalomyelitt. Referanselisten for dette dokumentet vises nedenfor.

  1. Lotze TE, Chadwick DJ. Acute disseminated encephalomyelitis in children: Pathogenesis, clinical features, and diagnosis. UpToDate, last updated Sep 01, 2020. UpToDate 
  2. Menge T, Kieseier BC, Nessler S et. al. Acute disseminated encephalomyelitis: an acute hit against the brain. Curr Opin Neurol 2007; 20: 247-54. PubMed 
  3. Brenton JN. Acute disseminated encephalomyelitis. Medscape, last updated Nov 08, 2018. emedicine.medscape.com 
  4. Dale RC, Branson JA. Acute disseminated encephalomyelitis or multiple sclerosis: can the initial presentation help in establishing a correct diagnosis? Arch Dis Child 2005; 90: 636-9. PubMed 
  5. Pohl D, Alper G, Van Haren K, et al. Acute disseminated encephalomyelitis: Updates on an inflammatory CNS syndrome. Neurology. 2016;87(9 Suppl 2):S38-S45. PMID: 27572859 PubMed 
  6. Chen Y, Ma F, Xu Y, Chu X, Zhang J.. Vaccines and the risk of acute disseminated encephalomyelitis. Vaccine 2018; 36: 3733-9. pmid:29784468 PubMed 
  7. Krupp LB, Tardieu M, Amato MP, et al. International Pediatric Multiple Sclerosis Study Group criteria for pediatric multiple sclerosis and immune-mediated central nervous system demyelinating disorders: revisions to the 2007 definitions. Mult Scler 2013; 19:1261. PubMed 
  8. Cole J, Evans E, Mwangi M, Mar S. Acute Disseminated Encephalomyelitis in Children: An Updated Review Based on Current Diagnostic Criteria. Pediatr Neurol 2019; 100:26. PubMed 
  9. Oksuzler YF, Cakmakci H, Kurul S. Diagnostic value of diffusion-weighted magnetic resonance imaging in pediatric cerebral diseases. Pediatr Neurol 2005; 32: 325-33. PubMed 
  10. Lotze TE, Chadwick DJ. Acute disseminated encephalomyelitis in children: Treatment and prognosis. UpToDate, last updated Dec 08, 2020. UpToDate 
  11. Alper G. Acute disseminated encephalomyelitis. J Child Neurol 2012; 27:1408. PubMed 
  12. Khurana DS, Melvin JJ, Kothare SV, et al. Acute disseminated encephalomyelitis in children: discordant neurologic and neuroimaging abnormalities and response to plasmapheresis. Pediatrics 2005; 116:431. Pediatrics 
  13. Iype M, Ts A, Kunju PM, et al. Factors Related to Long Term Motor, Behavioral, and Scholastic Outcome in Children with Acute Disseminated Encephalomyelitis. Pediatr Neurol 2018; 89:49. PubMed