Multippel sklerose (MS)
Sist oppdatert: Sist revidert:
Sist revidert av:Rune Midgard
Definisjon:
MS karakteriseres klinisk av avgrensede episoder med fokale angrep på hjernen, synsnervene og ryggmargen, alternativt en gradvis økning av funksjonstap (forverring eller progresjon), eller kombinasjoner av disse
Forekomst:
Cirka 10 000 personer lever med MS i Norge. Vanlig alder for symptomdebut er 20–45 år og mer enn dobbelt så mange kvinner som menn rammes
Symptom:
Synsforstyrrelse, dobbeltsyn, sensibilitetsforstyrrelse, kraftsvikt eller lammelser, koordinasjonsvansker, blærefunksjonsforstyrrelser
Kliniske funn:
Typisk er sentrale lammelser, temporeduksjon, koordinasjonsforstyrrelser og flekkvise sensibilitetsutfall
Diagnostikk:
Diagnosen baseres på anamnese og klinisk nevrologisk undersøkelse, MR og analyse av spinalvæske
Behandling:
Legemiddelbehandling mot akutte attakker, samt forebygging av attakkrate og utvikling av uførhet, symptomatisk behandling og rehabilitering
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- Rune Midgard, dr. med., overlege og førsteamanuensis II emeritus, NTNU
- Ingard Løge, spesialist allmennmedisin, redaktør NEL
Tidligere fagmedarbeidere
- Espen Dietrichs, professor og avdelingsoverlege, Universitetet i Oslo og Nevrologisk avdeling, Rikshospitalet, Oslo