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Rakitt - engelsk syke

Rakitt, også kalt engelsk syke, skyldes langvarig mangel på vitamin D. De mest typiske forandringene er hevelser av bein i håndledd og ankler, hjulbenthet, smerter i armer og bein, og eventuelt hemmet lengdevekst.

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Del pasientinformasjon

Den ligger åpent tilgjengelig på NHI.no sammen annen relevant informasjon

https://nhi.no/sykdommer/barn/vekst-og-utvikling/rakitt-engelsk-syke/ 

Hva er rakitt?

Årsaker

Symptomer og tegn

Behandling

Behandling ved påvist rakitt

Forebygging

Prognose

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Kilder

Referanser

Dette dokumentet er basert på det profesjonelle dokumentet Rakitt. Referanselisten for dette dokumentet vises nedenfor.

  1. Wharton B, Bishop N. Rickets. Lancet 2003; 362: 1389-400. PubMed 
  2. Nield LS, Mahajan P, Joshi A, Kamat D. Rickets: Not a disease of the past. Am Fam Physician 2006; 74: 619-26. PubMed 
  3. Meyer HE, Falch JA, Søgaard AJ, Haug E: Vitamin D deficiency and secondary hyperparathyroidism and the association with bone mineral density in persons with Pakistani and Norwegian background living in Oslo, Norway; The Oslo Health Study. Bone 2004; 35: 412-7. PubMed 
  4. Braegger C, Campoy C, Colomb V, et al. Vitamin D in the healthy European paediatric population. J Pediatr Gastroenterol Nutr. 2013 Jun. 56(6):692-701. PMID: 23708639 PubMed 
  5. Salle BL, Devlin EE, Lapillonne A, Bishop NJ, Glorieux FH. Perinatal metabolism of vitamin D. Am J Clin Nutr 2000; 71: (suppl) 1317S-24S.
  6. Zamora SA, Rizzoli R, Belli DC, Slosman DO, Bonjour JP. Vitamin D supplementation during infancy is associated with higher bone mineral mass in prepubertal girls. J Clin Endocrinol Metab 1999; 84: 4541-44. PubMed 
  7. Wu S, Chun R, Gacad MA, Ren S, Chen H, Adams JS. Regulation of 1,25-dihydroxyvitamin D synthesis by intracellular vitamin D binding protein-1. Endocrinology 2002; 143: 4135. PubMed 
  8. Jan De Beur Suzanne M, Levine MA. Molecular pathogenesis of hypophosphatemic rickets. J Clin Endocrinol Metab 2002; 87: 2467-73. PubMed 
  9. Shore RM, Chesney RW. Rickets: Part II. Pediatr Radiol. 2013 Jan. 43(2):152-72. PMID: 23179485 PubMed 
  10. Uysall D, Kalayci AG, Baysal K. Cardiac functions in children with vitamin D deficiency rickets. Pediatr Cardiol 1999; 20: 283-86. PubMed 
  11. Shaw NJ, Pal BR. Vitamin D deficiency in UK Asian families: activating a new concern. Arch Dis Child 2002; 86: 147-49. PubMed 
  12. Thacher TD, Fischer PR, Pettifor JM, Lawson JO, Manaster BJ, Reading JC. Radiographic scoring method for the assessment of the severity of nutritional rickets. J Trop Pediatr 2000; 46: 132-39. PubMed 
  13. Thacher TD, Fischer PR, Pettifor JM. The usefulness of clinical features to identify active rickets. Ann Trop Paediatr 2002; 22: 229-37. PubMed 
  14. Bulloch B, Schubert CJ, Brophy PD, Johnson N, Reed MH, Shapiro RA. Cause and clinical characteristics of rib fractures in infants. Pediatrics 2000; 105: E48. Pediatrics 
  15. De‐Regil LM, Palacios C, Lombardo LK, Peña‐Rosas JP. Vitamin D supplementation for women during pregnancy. Cochrane Database of Systematic Reviews 2016, Issue 1. Art. No.: CD008873. DOI: 10.1002/14651858.CD008873.pub3. DOI 
  16. Krogvold L, Brunvand L, Bjerknes R. Hypokalsemi og rakitt. Generell veileder i pediatri. Sist revidert 2009. Siden besøkt 15.05.2019. www.helsebiblioteket.no 
  17. Pearce SH, Cheetham TD. Diagnosis and management of vitamin D deficiency. BMJ 2010; 340: b5664. pmid:20064851 PubMed 
  18. Helsedirektoratet. Spedbarnsernæring. Anbefalinger for tilførsel av energi og næringsstoffer til spedbarn 6-11 måneder. www.helsedirektoratet.no 
  19. Nordic Nutrition Recommendations 2012. Integrating nutrition and physical activity. Utgitt 11.03.2014. www.norden.org 
  20. Sanders KM, Stuart AL, Williamson EJ, et al. Annual high-dose oral vitamin D and falls and fractures in older women. A randomized controlled trial. JAMA 2010; 303: 1815-22. PubMed 
  21. Bakke Å, Tazmini K, Pretorius M, Lima K. Vitamin D-mangel. Nasjonal veileder i endokrinologi. Versjon 1.10. Dato publisert 05.03.2021. www.endokrinologi.no 
  22. Webb AR. Who, what, where and when-influences on cutaneous vitamin D synthesis. Prog Biophys Mol Biol 2006; 92: 17-25. PubMed 
  23. Den norske legeforening. Nyheter 2019. Solarium uegnet som kilde til vitamin D. www.legeforeningen.no 
  24. Jacobsen AT, Mosekilde L. D-vitamin-mangel hos etniske minoriteter. Ugeskr Læger 2005; 167: 33-4.
  25. Lerch C, Meissner T. Interventions for the prevention of nutritional rickets in term born children. Cochrane Database of Systematic Reviews 2007, Issue 4. Art. No.: CD006164. DOI: 10.1002/14651858.CD006164.pub2 DOI 
  26. Casey CF, Slawson DC, Neal LR. Vitamin D supplementation in infants, children, and adolescents. Am Fam Physician 2010; 81: 745-8. American Family Physician 
  27. McGrath J. Does 'imprinting' with low prenatal vitamin D contribute to the risk of various adult disorders? Med Hypotheses 2001; 56: 367-71. PubMed 
  28. Harvey NC, Holroyd C, Ntani G, et al. Vitamin D supplementation in pregnancy: a systematic review. Health Technol Assess. 2014 Jul;18(45):1-190. PMID: 25025896 PubMed