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Henoch-Schønleins purpura

Sist revidert:
Sist revidert av:


Definisjon:
Vaskulitt som affiserer små blodårer i hud, tarm, ledd og nyrer. Ingen klar etiologi, men infeksjon, medikament eller andre miljøfaktorer synes å virke utløsende.
Forekomst:
Rammer ca. 15/100.000 årlig. Barn i alderen 4-6 år er mest utsatt, og det er en liten overvekt blant gutter
Symptomer:
Symptomene er ofte forutgått av en luftveisinfeksjon, og kan oppstå gradvis eller brått. Typisk er papler som utvikles til petekkier, magesmerter, leddsmerter og glomerulonefritt.
Funn:
Undersøkelse viser petekkier på ekstremiteter, nates og perigenitalt. Hevelse i ledd forekommer
Diagnostikk:
Klinisk diagnose. Serum-IgA og -IgM er forhøyet hos 50%. Nesten halvparten utvikler hematuri og/eller proteinuri
Behandling:
Behandlingen tar sikte på symptomlindring, sykdommen klinger som regel av i løpet av 4 uker. Mindre enn 1% får kronisk nyresvikt
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  • Ingard Løge, spesialist i allmennmedisin, redaktør NEL

Tidligere fagmedarbeidere

  • Roald Bolle, overlege og 1. amanuensis, barneavdelingen, Regionsykehuset og Universitetet i Tromsø