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Kawasakis sykdom

Sist oppdatert: Sist revidert:
Sist revidert av:
Definisjon:
Akutt, febril, selvbegrensende systemisk vaskulitt av ukjent årsak som oftest rammer barn under 5 år. 
Forekomst:
I Sverige har man funnet en insidens på 2,9 per 100.000 barn under 16 år og 6,2 per 100.000 under fem år
Symptomer:
Feber av minst fem dagers varighet + fire av følgende fem funn:
Funn:
Konjunktivitt, makulopapuløst utslett, ensidig forstørrede cervicale lymfeknuter, slimhinneforandringer på lepper og i munnhule, rubor og ødem i hender og fotsåler
Diagnostikk:
Lab.prøver er ikke diagnostiske, men ofte foreligger leukocytose, forhøyet SR og CRP og trombocytose
Behandling:
I sykehus. Intravenøst immunglobulin kombinert med acetylsalisylsyre
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  2. Rypdal V, Songstad NT, Nyrnes SA, et al. Kawasakis sykdom. Akuttveileder i pediatri. Sist revidert 2021. www.helsebiblioteket.no  
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  13. Platt B, Belarski E, Manaloor J, et al. Comparison of Risk of Recrudescent Fever in Children With Kawasaki Disease Treated With Intravenous Immunoglobulin and Low-Dose vs High-Dose Aspirin. JAMA Netw Open 2020; 3: e1918565. pmid:31899532 PubMed  
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  18. Zhao QM, Chu C, Wu L, et al. Systemic Artery Aneurysms and Kawasaki Disease. Pediatrics 2019. pmid:31732547 PubMed  
  • Ingard Løge, spesialist allmennmedisin, redaktør NEL
  • Terje Johannessen, professor i allmennmedisin, Trondheim

Tidligere fagmedarbeidere

  • Kurt Østhuus Krogh, spesialist i barnesykdommer, Barne- og ungdomsklinikken, St. Olavs Hospital, Trondheim
  • Bengt Granström, överläkare, Barn-och ungdomsmedicinska kliniken, Skånes universitetssjukhus (Medibas)