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Polymyalgia rheumatica (PMR)

Sist oppdatert: Sist revidert:
Sist revidert av:

Definisjon:
Er en inflammatorisk revmatisk tilstand. Ukjent årsak
Forekomst:
I Norge hos ca. 110 per 100 000 per år. Vanligvis over 50 år. Særlig hyppig i Skandinavia
Symptomer:
De mest fremtredende symptomene er bilaterale skulder- og/eller bekkensmerter, morgenstivhet og generell sykdomsfølelse.
Funn:
Få typiske funn, men ofte ømhet i muskulaturen 
Diagnostikk:
Akutt fase reaktanter som SR og CRP er ofte forhøyet
Behandling:
Kortikosteroider. Vanlig startdose er 12,5-25 mg prednisolon daglig
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  9. Gilden D, White T, Khmeleva N, et al. Prevalence and distribution of VZV in temporal arteries of patients with giant cell arteritis. Neurology 2015. DOI: 10.1212/WNL.0000000000001409 DOI  
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  13. González-Gay MA, Pina T. Giant cell arteritis and polymyalgia rheumatica: an update. Curr Rheumatol Rep. 2015 Feb;17(2):6. PMID: 25618572 PubMed  
  14. Macchioni P1, Boiardi L, Catanoso M, Pazzola G, Salvarani C. Performance of the new 2012 EULAR/ACR classification criteria for polymyalgia rheumatica: comparison with the previous criteria in a single-centre study. Ann Rheum Dis 2014; 73: 1190-3. pmid:24297384 PubMed  
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  26. Wu J, Keeley A, Mallen C et al. Incidence of infections associated with oral glucocorticoid dose in people diagnosed with polymyalgia rheumatica or giant cell arteritis: a cohort study in England. CMAJ 2019; 191: E680-8. pmid:31235489 PubMed  
  27. Faurschou M, Ahlstrom MG, Lindhardsen J, et al. Risk of Diabetes mellitus among patients diagnosed with giant cell arteritis or granulomatosis with polyangiitis: Comparison with the general population. J Rheumatol. 2016 . PMID:27744394 PubMed  
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  30. Muller S, Hider SL, Belcher J, et al. Is cancer associated with polymyalgia rheumatica? A cohort study in the general practice research database. Ann Rheum Dis 2014; 73: 1769:73. doi:10.1136/annrheumdis-2013-203465 DOI  
  31. Dasgupta B, Borg FA, Hassan N, et al.; BSR and BHPR Standards, Guidelines and Audit Working Group. BSR and BHPR guidelines for the management of polymyalgia rheumatica. Rheumatology (Oxford). 2010;49(1):186–190.
  • Peter D. Jost, spesialist i allmennmedisin, redaktør NEL, Trondheim

Tidligere fagmedarbeidere

  • Gunnar Husby, professor i revmatologi, Oslo Sanitetsforenings Revmatismesykehus, Universitetet i Oslo og Rikshospitalet, Oslo